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Infections can be transmitted by contact, but also by inhalation or ingestion. The most common pathogen in horses is Streptococcus equi subsp. equi, which is also the cause of the condition called strangles [13Hemsworth A. The Strangles complex: a review of the aetiology and clinical presentations. Equine Vet J 1987; 18(2): 47-52.[ ] [PMID: 3856317] ]. Influenza virus, equine herpes virus type 1, equine herpes virus type 3, equine arteritis virus, parainfluenza virus and equine adenovirus are most commonly transmitted via the respiratory tract [14Cochran DM, Mitchell SS, Posnett WL, et al. Clinical characteristics and laboratory findings in equine herpes virus type 1 encephalitis in horses. J Vet Intern Med 2000; 14(4): 596-604.], whereas equine polyomavirus [15Witzel R, Goodrich TH, Krawczak TW, et al. Serologic response of shetland ponies to infection with equine polyomavirus type 1. J Vet Intern Med 2000; 14(1): 40-7.], equine encephalomyelitis virus [16Gutierrez S, Taylor A, Chuang P, et al. Anecdotal reports of equine herpesvirus type 1-associated respiratory disease in horses in the United States. 2001. J Vet Intern Med 2001; 15(2): 207-15.], equine monocytic ehrlichiosis [17Monfort R, King M, Goring J, et al. Repeat febrile episodes in horses: prevalence, association with mucosal disease, and response to antibiotic treatment. J Vet Intern Med 1996; 10(5): 516-23.], equine herpes virus type 4 [18Budd L, Mackenzie W, Williams K, et al. The pathogenesis of equine herpesvirus type 4 infection in the horse. J Vet Intern Med 1994; 8(1): 45-53.], equine infectious anemia [19Waters D, Osterhaus AD, Humbert J. Equine infectious anemia: a review. South Vet Med 1990; 83(2): 97-104.] and pathogenic Escherichia coli infections are transmitted by ingestion.
The AAEP Vaccination Guidelines Review Task Force recommends inactivated vaccines against equine herpesvirus and equine influenza virus as a rational and effective strategy for the prevention of infectious diseases in adult horses. While the target population for vaccination with equine influenza virus inactivated vaccines is adult horses, the majority of which are at risk, infection in horses younger than 2 years of age should be prevented with a combination of a live attenuated influenza vaccine and a vaccine against equine influenza virus. Vaccination of horses older than 2 years of age can be considered for the prevention of equine influenza virus infections in horses. However, for many years, the ability of the available equine influenza virus inactivated vaccines to provide sufficient immunity in the adult horse population has been a concern.
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